Production of Single Contracting Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes: Matrigel Mattress Technique
نویسندگان
چکیده
منابع مشابه
Matrigel Mattress: A Method for the Generation of Single Contracting Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
RATIONALE The lack of measurable single-cell contractility of human-induced pluripotent stem cell-derived cardiac myocytes (hiPSC-CMs) currently limits the utility of hiPSC-CMs for evaluating contractile performance for both basic research and drug discovery. OBJECTIVE To develop a culture method that rapidly generates contracting single hiPSC-CMs and allows quantification of cell shortening ...
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ژورنال
عنوان ژورنال: Current Protocols in Stem Cell Biology
سال: 2017
ISSN: 1941-7322,1938-8969
DOI: 10.1002/cpsc.32